The Don S. Fredrickson Lipid Research Conference, formerly the Southeast Lipid Research Conference (SELRC), brings together scientists and trainees investigating the impact of lipid and lipoprotein metabolism on the development and treatment of cardiometabolic disease. The conference is committed to new investigators and trainees from diverse backgrounds and topics in lipid and lipoprotein metabolism. The Fredrickson Conference employed an institutional host model in 2016 at the University of Kentucky in conjunction with the Saha Cardiovascular Research Center and Gill Heart & Vascular Center Cardiovascular Research Day. The Fredrickson Conference has since been hosted by Vanderbilt University (2018), the University of Cincinnati (2019), and again at the University of Kentucky (2021). Future sites include Duke University / University of North Carolina (2022), Vanderbilt University (2023) and the Medical College of Wisconsin (2024).