Larry Rudel Award
Lawrence 'Larry' L. Rudel, PhD (1941-2019) was a renowned lipid scientist and biochemist who during his 50-year career published 243 peer-reviewed manuscripts, 19 book chapters, and delivered 164 scientific presentations. He joined the faculty at Wake Forest University School of Medicine (WFUSM) in 1973 and retired from the same institution in 2018 as Professor of Internal Medicine-Section on Molecular Medicine and Biochemistry. Larry had a distinguished record of service to the scientific community which included serving on the Editorial Board of the Journal of Lipid Research for 36 years, as Chair of the Metabolism Study Section for the National Institutes of Health (NIH), and as Chair of the Arteriosclerosis, Thrombosis and Vascular Biology (ATVB) Council of the American Heart Association (AHA). Most importantly he directly mentored seventeen PhD students, three MS students, and twenty-nine postdoctoral fellows, and indirectly impacted countless trainees and faculty by fostering an extremely rich learning environment.
To honor his legacy of trainee mentoring and development, the Larry Rudel Lipid Sciences Award Fund has been established to support a national award program that recognizes trainee excellence in lipid research. The Lipid Sciences Award will be given annually at the Fredrickson Lipid Research Conference (formerly the South East Lipid Research Conference) to an eligible graduate student or post-doctoral scholar with the best abstract presentation. The Saha Cardiovascular Research Center at The University of Kentucky is the administrative home for both the conference and the award.
Larry Rudel Award Lectures and Winners
2021
Lucas J. Osborn, PhD | Cleveland Clinic
A gut microbial metabolite of dietary polyphenols reverses obesity-driven hepatic steatosis
Wen Dai, MD |Medical College of Wisconsin
Silencing hepatocyte tissue plasminogen activator increases plasma apoB lipoprotein-cholesterol by promoting MTP-mediated VLDL lipidation
Danny Orabi, MD, PhD | Cleveland Clinic**
The Serine Hydrolase ABHD6 is a Therapeutic Target in Obesity-Associated Hepatocellular Carcinoma
2022
Natalia Do Couto | University of Illinois at Chicago
Cholesterol-Induced Suppression of Kir2.1 Contributes to Atherosclerotic Plaque Development
Kathryn Gunn | University of North Carolina at Chapel Hill**
Active Lipoprotein Lipase Dimer Revealed by CryoEM
Clint Upchurch | University of Virginia
AAV8-mediated expression of scFv-E06 to target oxidized phosphatidylcholines is an effective therapeutic intervention to prevent progression to hepatic fibrosis
2023
Nour Mouannes | Cleveland Clinic
The Ability of Dietary Polyunsaturated Fatty Acids to Protect Against Hepatic Inflammation and Non-Alcoholic Steatohepatitis is Dependent on Gut Microbes
Mikala Zelows | University of Kentucky
Carnitine Palmitoyltransferase 1a Modulates Hepatic Lipid and Lipoprotein Metabolism
Anh Cao | Harvard University**
Long Acyl Chains as a Primal Molecular Cue for Identifying Potential Threats
**Winner